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AFE49I30
  • AFE49I30
  • AFE49I30

AFE49I30

ACTIVE

Ultra-low-power integrated AFE for wearable optical biosensing with FIFO, I2C and ECG

Texas Instruments AFE49I30 Product Info

1 April 2026 1

Parameters

Applications

ECG patch, HRV, Optical-HRM for wearables, PTT-based blood pressure, Patient monitoring, Sleep study monitor, SpO2, Vo2 max

Number of input channels

4

Resolution (Bits)

22

Number of LEDs

6

Interface type

I2C

Operating temperature range (°C)

-40 to 85

Rating

Catalog

Package

DSBGA (YZ)-30-4.8 mm² 2.4 x 2

Features

  • Supports signal acquisition of up to 24 phases
  • Flexible allocation of 6 LED, 4 PD in each PPG phase
  • Synchronized PPG/ECG signal acquisition with each phase configurable as PPG or ECG, and at different data rates
  • Synchronized PPG/ECG supports up to 1 kHz data rate
  • ECG-only mode supports up to 4 kHz data rate
  • PPG signal chain:
    • System SNR up to 108-dB at 16 µA PD current
    • Low current for continuous operation on a wearable device with a typical value: 15 µA for an LED, 20 µA for the receiver
  • PPG Transmitter:
    • Supports common anode LED configuration
    • 8-Bit programmable LED current with range adjustable from 25 mA to 250 mA
    • Mode to fire two LEDs in parallel with independent per-phase current control
    • Programmable LED on-time per-phase
    • Simultaneous support of 6 LEDs for SpO2, HRM, or multi-wavelength HRM
  • PPG Receiver:
    • Supports 4 time-multiplexed photodiode inputs
    • 2 parallel receivers to sample two PD channels simultaneously
    • Individual ambient offset subtraction DAC at each TIA Input with 8-bit per-phase control and range adjustable up to 255-µA
    • Individual LED offset subtraction DAC at each TIA input with 5-bit per-phase control and
      15.5-µA range
    • Close to 100 dB ambient rejection up to 10 Hz
    • Noise filtering with programmable bandwidth
    • Transimpedance Gain: 3.7 kΩ to 1 MΩ
  • ECG Signal Chain
    • 1-lead ECG with RLD output for bias
    • INA gain programmable from 1.6 – 13
    • <1 µVrms input noise (in a 1-150 Hz bandwidth) at 4-kHz sample rate
    • Integrated 450 Hz Low Pass Filter
    • AC, DC lead-off detect with 3.125-100 nA current and programmable interrupt
  • Supports external clock and internal oscillator modes
  • Option to acquire data synchronized with a system master clock
  • Automatic cancellation of DC from ambient, LED
  • FIFO with 128-sample depth
  • I2C interface
  • 2.6-mm × 2.1-mm DSBGA, 0.4-mm pitch
  • Supplies: Rx: 1.7 V-1.9 V (LDO bypass); 1.9 V-3.6 V (LDO enabled), Tx: 3 V-5.5 V, IO: 1.7-3.6 V
  • Supports operation with 2 supplies - 1.8 V, 5 V
  • Supports signal acquisition of up to 24 phases
  • Flexible allocation of 6 LED, 4 PD in each PPG phase
  • Synchronized PPG/ECG signal acquisition with each phase configurable as PPG or ECG, and at different data rates
  • Synchronized PPG/ECG supports up to 1 kHz data rate
  • ECG-only mode supports up to 4 kHz data rate
  • PPG signal chain:
    • System SNR up to 108-dB at 16 µA PD current
    • Low current for continuous operation on a wearable device with a typical value: 15 µA for an LED, 20 µA for the receiver
  • PPG Transmitter:
    • Supports common anode LED configuration
    • 8-Bit programmable LED current with range adjustable from 25 mA to 250 mA
    • Mode to fire two LEDs in parallel with independent per-phase current control
    • Programmable LED on-time per-phase
    • Simultaneous support of 6 LEDs for SpO2, HRM, or multi-wavelength HRM
  • PPG Receiver:
    • Supports 4 time-multiplexed photodiode inputs
    • 2 parallel receivers to sample two PD channels simultaneously
    • Individual ambient offset subtraction DAC at each TIA Input with 8-bit per-phase control and range adjustable up to 255-µA
    • Individual LED offset subtraction DAC at each TIA input with 5-bit per-phase control and
      15.5-µA range
    • Close to 100 dB ambient rejection up to 10 Hz
    • Noise filtering with programmable bandwidth
    • Transimpedance Gain: 3.7 kΩ to 1 MΩ
  • ECG Signal Chain
    • 1-lead ECG with RLD output for bias
    • INA gain programmable from 1.6 – 13
    • <1 µVrms input noise (in a 1-150 Hz bandwidth) at 4-kHz sample rate
    • Integrated 450 Hz Low Pass Filter
    • AC, DC lead-off detect with 3.125-100 nA current and programmable interrupt
  • Supports external clock and internal oscillator modes
  • Option to acquire data synchronized with a system master clock
  • Automatic cancellation of DC from ambient, LED
  • FIFO with 128-sample depth
  • I2C interface
  • 2.6-mm × 2.1-mm DSBGA, 0.4-mm pitch
  • Supplies: Rx: 1.7 V-1.9 V (LDO bypass); 1.9 V-3.6 V (LDO enabled), Tx: 3 V-5.5 V, IO: 1.7-3.6 V
  • Supports operation with 2 supplies - 1.8 V, 5 V

Description

The AFE49I30 is an analog front-end for optical bio-sensing/ PPG and ECG measurement applications. The device supports up to six switching light-emitting diodes (LEDs) and up to four photodiodes. Up to 24 signal phases can be defined and the PPG or ECG signals can be acquired from each phase in a synchronized manner.

The AFE49I30 is an analog front-end for optical bio-sensing/ PPG and ECG measurement applications. The device supports up to six switching light-emitting diodes (LEDs) and up to four photodiodes. Up to 24 signal phases can be defined and the PPG or ECG signals can be acquired from each phase in a synchronized manner.

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